Molecular Formula | C15H30O7 |
Molar Mass | 322.39 |
Density | 1.04746 g/mL |
Boling Point | 406.8±35.0 °C(Predicted) |
Appearance | Morphological liquid |
pKa | 14.36±0.10(Predicted) |
Storage Condition | 2-8°C |
Refractive Index | n/D 1.4492 |
Downstream Products | Bromo-PEG4-t-butyl ester H2N-PEG4-tBu |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 3.102 ml | 15.509 ml | 31.018 ml |
5 mM | 0.62 ml | 3.102 ml | 6.204 ml |
10 mM | 0.31 ml | 1.551 ml | 3.102 ml |
5 mM | 0.062 ml | 0.31 ml | 0.62 ml |
biological activity
Hydroxy-PEG4-(CH2)2-Boc is an ADC linker used to synthesize antibody-coupled drugs (ADC), Hydroxy-PEG4-(CH2)2-Boc is derived from a patented WO2004008101A2 (compound 191). Hydroxy-PEG4-(CH2)2-Boc can also be used as PROTAC linker for PROTAC synthesis..
target
Non-cleavable
Alkyl/ether
PEGs
in vitro study
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.